Expert Column - Preventing Adverse Drug Reactions

“One-Size Fits All” Drugs

Are medications currently developed and prescribed with sufficient affectionateness for being type?
One-size fits all dosing provides no trait for adjusting doses to fit person patients and, therefore, is medically irrational.
Yet, one-size fits all drugs seem more popular than ever.

For occurrence, loratadine (Claritin) is the most popular antihistamine and the numeral 9 top-selling drug in Terra firma. The volume unit dose is 10 mg regardless of whether a case is 100 or 300 pounds, age 25 or 95 — or 6 old age old.
Yet, the Physicians’ Desk Computer address (PDR) states that in healthy subjects 66-78 eld old, the ECF grade and AUC of loratadine are 50% greater and the mean murder half-life is significantly longer than in younger patients. Even greater pharmacokinetic deviations would be expected in seniors with other condition, persons taking other medications, or those over age 78.
This is a part of article Expert Column - Preventing Adverse Drug Reactions Taken from "Generic Claritin (Loratadine)" Information Blog